Tidigare studier har fokuserat på barn och deras familjers upplevelser i samband med en hematologisk malignitet, framförallt leukemi. Hematologiska maligniteter är ett samlingsnamn för leukemi och några andra blodsjukdomar. Prevalensen för sjukdomarna ökar och främst vuxna drabbas. Syftet med studien var att beskriva patienters upplevelser av att leva med en hematologisk malignitet. Metoden för denna litteraturöversikt var kvalitativ.

The RECK gene is a relatively new discovered gene with important implications for cancer research. The research has been primarily concentrated on the human gene with the ultimate aim to identify the invasive characteristics. Up regulated RECK is linked to significantly prolonged survival rates in patients with severe forms of malignancies. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix. The RECK protein is a membrane-bound glycoprotein that inhibit matrix metalloproteinases which has the function of breaking down the ECM. There is a significant correlation between RECK gene expression and the formation of new vessels, presumably via the mediation of VEGF which is an important and powerful inducer of angiogenesis.

Pyometra, chronic purulent metritis in metoestrus, is a common disease in intact bitches. About 25% of all bitches in Sweden have contracted the disease before ten years of age. Clinical signs of the disease are varied, and the course may be either slow or acute. The diagnosis is most commonly made by radiographical or ultrasonographical examination of the abdomen in combination with blood biochemical and hematological analyses. The safest and most efficient treatment of pyometra is surgical ovariohysterectomy.There is room for improvement of both diagnostic tools and possible prognostic indicators for pyometra.Mast cells are large leucocytes, with granule that contain inflammatory mediators.

?Tollarsjuka? is a disease with a suspected immunopathological background seen in Nova Scotia duck tolling retrievers. Pyrexia, lameness, stiffness and joint- or musclepain are typical clinical signs. The purpose of this study is to describe case histories from dogs with a possible evidence of ?tollarsjuka?. 18 private dogs were included in this report. Generalised stiffness, lameness and fatigue were the most frequent manifestations of the disease.

Hematology-instruments that analyze blood cells can at specific cases be followed by manual counting with a hemocytometer. The plastic hemocytometer which has a fixed coverslip and is assigned for disposable use, appears to reduce the problems arising from the use of the traditional glass hemocytometer, for instance coverslip-application difficulty and dust particles. Capillary whole blood sampling may be useful for patients at the emergency department and in addition, a smaller volume of blood is taken compared to venous blood sampling. This study will focus on the platelet- and leukocyte count (PLT and WBC) in venous and capillary blood, in order to compare the plastic- and glass hemocytometers with Sysmex XN-2000 (Sysmex Corporation, Kobe, Japan), and verify if capillary whole blood sampling can be used for the measurement of these hematological parameters. 30 subjects donated both capillary- and venous blood samples and these blood samples were analyzed with glass- and plastic hemocytometers with Sysmex XN-2000 as the reference method.

Syfte: Syftet har varit att beskriva hur patienter uppfattar begreppet egenvård samt deras uppfattningar gällande information om egenvård.Metod: Empirisk studie med kvalitativ design. Strategiskt urval av åtta patienter som genomgått stamcellstransplantation. Datainsamling skedde genom semistrukturerade intervjuer.Resultat: Patienter uppfattar att egenvård är att ta hand om sig så att den egna fysiska samt psykiska hälsan främjas, utan inblandning av sjukvården. De flesta patienter uppfattade att informationen om egenvård hade varit tillfredsställande. Dock förekom svårigheter med att koppla ihop begreppet egenvård med den information som givits om egenvårdande åtgärder.

Phenylbutazone has been discussed in the world of the equestrian sport several times and different countries have diverse opinions on its use in competitions. The progressive list that permits phenylbutazone with plasma levels up to 8 µg/ml was presented at the FEI General Assembly in November 2009. The list was voted to be accepted, but later several countries realized the consequences and after protests the list was rejected and is going to be discussed again at the FEI General Assembly 2010. In this literature study I have studied the relationship between the concentrations of phenylbutazone in plasma and the effects on lameness. The purpose was to establish whether the limit of 8 µg/ml phenylbutazone in plasma affects the equestrian sport.

Introduction Malignant lymphoma is the most common haematological blood cancer diagnosis. In spring 2013 a questionnaire was handed out to patients with various haematological malignancies. The results showed that the patients requested more verbal and written information about their disease and treatment. Providing information about chemotherapy and how it affects the patient's quality of life is part of the nursing care. Communication between nurse and patient is very important to share experiences and knowledge with each other Aim The aim is to describe the information and communication patients with malignant lymphoma demand, based on their own experience, in meeting with the nurse before and during curative chemotherapy treatment at a haematology outpatient clinic.

Serum thymidine kinase 1 (TK1) activity is used as a tumor marker in disease monitoring in veterinary and human medicine. TK1, an intracellular enzyme, is involved in a salvage pathway of DNA precursor synthesis. TK1 is used in DNA precursor production by catalyzing the transfer of the gamma-phosphate-group from a phosphate-donor to the 5?- hydroxyl-group of thymidine forming thymidine-monophosphate. Nucleoside monophosphosphates are finally converted into thymidine-triphosphates. TK1 activity significantly rises in the G1 and the S phase of the cell cycle.

The dog has often served as a model animal for humans in scientific studies. This is due to the fact that dogs are susceptible to a wide range of diseases which also affect humans. One example is cancer, a condition that affects dogs as well as owners. Neoplastic diseases account for 18-23 % of all deaths in dogs (Bonnet et al., 2005 and Jagielski et al., 2002). Mammary tumor, or tumor of the breast, is the most common tumor form in intact dogs and women (Im et al., 2013). Mammary tumors originate in the udder, and are classified according to their histological characteristics.